We are working toward a cultural transformation that will drive the way we design, consume and dispose of products, with a focus on "better, not more." We use research, knowledge creation, education, organizing, and mobilization to make this change. We test products to educate and drive reformulation, advocate for Green Chemistry training and education, leverage the size and opinion leader status of health care, and frame our issues in terms of health, with a special focus on children's health. A toxic material economy impacts the most vulnerable and powerless. We push manufacturers to make safer products and address the inequities in our material economy.